Study Specific Websites
Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow
Failure Syndromes (IBMFS)
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Inherited
bone marrow failure syndromes (IBMFS) are rare disorders in which there
is usually some form of aplastic anemia (failure of the bone marrow to
produce blood), associated with a family history of the same disorder.
Familial
Testicular Cancer Study
- Testicular cancer is the most common form of cancer in young men
ages 15 to 35. It accounts for about 1 percent of all cancer in men,
with approximately 7,400 cases diagnosed in the United States every
year. It is much more common in white males than in black males.
Breast Imaging
Study
- Women who are at high genetic risk of cancer because they have a
mutation in one of the BReast CAncer susceptibility genes, BRCA1 or
BRCA2, are at increased risk of developing breast cancer. Many high-risk
women develop breast cancer before the age of 50. For these women, cancer
risk is managed through vigilant surveillance, in hopes of identifying
the disease at an early stage.
Ovarian
Cancer Prevention and Early Detection Study
- This is a national prospective study of women who are at increased
risk of ovarian cancer, either because they or a close relative have
a mutation in the BRCA1 or BRCA2 genes, or because they have a strong
family history of breast and/or ovarian cancer. This study is being
led by the Clinical Genetics Branch, in close collaboration with the
Gynecologic Oncology Group and the
Cancer Genetics Network.
After discussion with their own health care providers, high-risk women
will choose either risk-reducing surgery or ovarian cancer screening
to manage their ovarian cancer risk. Both groups of women will be followed
for five years to assess the impact of their choice on cancer occurrence
and quality of life.
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CGB Study Brochures
All brochures are PDF format
WEB-Based Lectures by Clinical Genetics Branch
Staff
Hereditary Breast/Ovarian Cancer Study
Newsletters
All Newsletters are PDF format
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