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Cellular track model of biological damage to mammalian cell cultures from galactic cosmic raysThe assessment of biological damage from the galactic cosmic rays (GCR) is a current interest for exploratory class space missions where the highly ionizing, high-energy, high-charge ions (HZE) particles are the major concern. The relative biological effectiveness (RBE) values determined by ground-based experiments with HZE particles are well described by a parametric track theory of cell inactivation. Using the track model and a deterministic GCR transport code, the biological damage to mammalian cell cultures is considered for 1 year in free space at solar minimum for typical spacecraft shielding. Included are the effects of projectile and target fragmentation. The RBE values for the GCR spectrum which are fluence-dependent in the track model are found to be more severe than the quality factors identified by the International Commission on Radiological Protection publication 26 and seem to obey a simple scaling law with the duration period in free space.
Document ID
19910007668
Acquisition Source
Legacy CDMS
Document Type
Technical Publication (TP)
Authors
Cucinotta, Francis A. (Rockwell International Corp. Houston, TX., United States)
Katz, Robert (Nebraska Univ. Lincoln., United States)
Wilson, John W. (NASA Langley Research Center Hampton, VA., United States)
Townsend, Lawrence W. (NASA Langley Research Center Hampton, VA., United States)
Nealy, John E. (NASA Langley Research Center Hampton, VA., United States)
Shinn, Judy L. (NASA Langley Research Center Hampton, VA, United States)
Date Acquired
September 6, 2013
Publication Date
February 1, 1991
Subject Category
Space Radiation
Report/Patent Number
L-16831
NAS 1.60:3055
NASA-TP-3055
Accession Number
91N16981
Funding Number(s)
PROJECT: RTOP 199-04-16-11
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

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