Regional aquifer systems in the Great Basin consist of carbonate-rock aquifers in the eastern Great Basin and basin-fill aquifers throughout the region. In the carbonate-rock aquifers, barriers to regional flow include Precambrian crystalline basement, upper Precambrian and Lower Cambrian clastic sedimentary rocks, and Jurassic to Tertiary granitic rocks. Basin-fill aquifers are connected to carbonate-rock aquifers in the eastern Great Basin and can be hydraulically connected with each other throughout the Great Basin.